What to Expect During Oxycodone Detox: Timeline, Symptoms & Recovery Tips

Oxycodone—sold under brand names like OxyContin®, Percocet®, and Roxicodone®—is one of the most commonly prescribed (and misused) opioids in the U.S. While effective for pain management, it carries a high risk of dependence and addiction. Once the body becomes physically dependent, stopping oxycodone can trigger intense withdrawal symptoms.

If you’re considering oxycodone detox for yourself or a loved one, here’s what you can expect—and how to prepare for a safer, more supported recovery.

Why Oxycodone Withdrawal Happens

When you take opioids regularly, your brain adjusts to their presence. Over time, it stops producing natural pain-relieving chemicals, relying entirely on the drug. When you remove it, your body goes into a state of shock as it tries to rebalance itself—this is withdrawal.

Oxycodone Withdrawal Timeline

Day 1–2 (Early Withdrawal):

• Anxiety

• Sweating

• Muscle aches

• Restlessness

• Runny nose

• Cravings

Day 3–5 (Peak Symptoms):

• Nausea and vomiting

• Abdominal cramping

• Insomnia

• Dilated pupils

• Goosebumps

• Rapid heart rate

Day 6–10 (Tapering Down):

• Lingering insomnia

• Fatigue

• Emotional sensitivity

• Mood swings

Post-Acute Withdrawal (Weeks 2–6):

• Low motivation

• Depression

• Anxiety or cravings under stress

How Salterra OC Detox Can Help

At Salterra OC Detox in Orange County, we provide 24/7 medical supervision, MAT (Medication-Assisted Treatment) like Suboxone®, and trauma-informed therapy to make detox as safe and manageable as possible. We also offer:

• Holistic recovery support

• Sleep and nutrition stabilization

• Breathwork, yoga, and grounding techniques

• Individual and group therapy

Final Thoughts

Detoxing from oxycodone is a courageous first step. It’s not easy—but with the right medical support, it’s absolutely possible. Whether your use began with a prescription or evolved into something more, healing starts the moment you ask for help.